Miho Koizumi   Hikaru Eto   Mai Saeki   Masahide Seki   Tsuyoshi Fukushima   Shoichiro Mukai   Hisamitsu Ide   Yasuyuki Sera   Masayuki Iwasaki   Yutaka Suzuki   Atsushi Tohei   Yusuke Kishi   Hiroaki Honda   
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36(12) e22662 2022年12月
Recent studies have demonstrated that epigenetic modifications are deeply involved in neurogenesis; however, the precise mechanisms remain largely unknown. To determine the role of UTX (also known as KDM6A), a demethylase of histone H3K27, in neur...
The Journal of veterinary medical science 84(3) 445-453 2022年3月 [査読有り]
A non-narcotic anesthetic combination (Me/Mi/Bu) of medetomidine (Me), midazolam (Mi), and butorphanol (Bu) has been recommended as the injectable anesthesia in mice. An original dose of Me/Mi/Bu (0.3/4.0/5.0 mg/kg) has provided sufficient anesthe...
The Journal of veterinary medical science 2020年10月 [査読有り]
Hypothermia during anesthetic events is a common adverse effect of anesthesia in laboratory animals. In particular, small rodents such as mice is susceptible to hypothermia during anesthetic events. Therefore, the animals will need additional ther...
JOURNAL OF VETERINARY MEDICAL SCIENCE 73(7) 901-906 2011年7月
It is known that pica, the consumption of non-nutritive substances such as kaolin, can be induced by administration of toxins or emetic agents in rats. In the present study, we examined the effects of intraperitoneal (i.p.) administration of cyclo...
Shu-ichi Kojima   Atsushi Tohei   Masashi Ikeda   
BRITISH JOURNAL OF PHARMACOLOGY 162(5) 1179-1185 2011年3月
BACKGROUND AND PURPOSE
Melatonin is involved in the regulation of colonic motility, and sensation, but little is known about the influence of melatonin on 5-hydroxytryptamine (5-HT) release from colonic mucosa. A tachykinin NK2 receptor-selective ...
The rdw rat is a hereditary hypothyroid strain isolated from Wistar-Imamichi rats. In the present study, adrenocorticotropic hormone (ACTH) and corticosterone responses to restraint stress (120 min) were examined in rdw adult male rats. ACTH respo...