Miho Koizumi   Hikaru Eto   Mai Saeki   Masahide Seki   Tsuyoshi Fukushima   Shoichiro Mukai   Hisamitsu Ide   Yasuyuki Sera   Masayuki Iwasaki   Yutaka Suzuki   Atsushi Tohei   Yusuke Kishi   Hiroaki Honda   
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36(12) e22662 2022年12月
Recent studies have demonstrated that epigenetic modifications are deeply involved in neurogenesis; however, the precise mechanisms remain largely unknown. To determine the role of UTX (also known as KDM6A), a demethylase of histone H3K27, in neur...
The Journal of veterinary medical science 84(3) 445-453 2022年3月 [査読有り]
A non-narcotic anesthetic combination (Me/Mi/Bu) of medetomidine (Me), midazolam (Mi), and butorphanol (Bu) has been recommended as the injectable anesthesia in mice. An original dose of Me/Mi/Bu (0.3/4.0/5.0 mg/kg) has provided sufficient anesthe...
The Journal of veterinary medical science 2020年10月 [査読有り]
Hypothermia during anesthetic events is a common adverse effect of anesthesia in laboratory animals. In particular, small rodents such as mice is susceptible to hypothermia during anesthetic events. Therefore, the animals will need additional ther...
A Tohei   Y Mogi   H Kon   R Hokao   M Shinoda   
EXPERIMENTAL ANIMALS 52(5) 437-439 2003年10月
In the present study, we used closed colony-Wistar-Imamichi (WI), inbred W1 and Long Evans (LE) adult male rats to examine the secretion of ACTH and corticosterone in response to restraint stress. Blood (0.3 ml) was withdrawn through a jugular can...
R Ohta   M Shirota   A Tohei   K Taya   
HORMONES AND BEHAVIOR 42(2) 116-125 2002年9月
Hatano high- and low-avoidance (in a two-way active avoidance task) animals (HAA and LAA, respectively) were successfully selected from a Sprague-Dawley rat population. Pup growth of both strains was dependent on the maternal strain in a cross-fos...