The Journal of veterinary medical science 83(12) 1918-1927 2021年11月 [査読有り]
Pulmonary hypertension (PH) is a common comorbidity in dogs with myxomatous mitral valve disease (MMVD), and can induce various changes in the right heart, such as right ventricular (RV) hypertrophy, dilatation, and dysfunction. We hypothesized th...
American journal of veterinary research 82(11) 865-871 2021年11月 [査読有り]
OBJECTIVE: To evaluate the influence of manual ventilation-controlled respiration on right ventricular (RV) pressure-volume loop-derived and echocardiographic variables in dogs. ANIMALS: 8 healthy, anesthetized Beagles. PROCEDURES: In a prospectiv...
Post-capillary pulmonary hypertension (PH) is a life-threatening complication in dogs with myxomatous mitral valve disease (MMVD). An increase in pulmonary vascular resistance (PVR) is associated with post-capillary PH progression. In humans, PVR ...
Frontiers in Veterinary Science 8 727155-727155 2021年8月 [査読有り]
<bold>Background:</bold> Pulmonary hypertension (PH) is a life-threatening disease in dogs characterized by an increase in pulmonary arterial pressure (PAP) and/or pulmonary vascular resistance. Right ventricle adapts to its pressure overload thro...
Journal of Immunology Research 2021 1-20 2021年8月 [査読有り]
Adipose tissue-derived mesenchymal stem cells (ADSCs) have anti-inflammatory and immunomodulatory characteristics. Many studies have suggested that the immunomodulation of ADSCs is largely mediated by secreted paracrine factors. Various factors ar...