Eiichi Kawakami   Masanori Kobayashi   Akiko Ikeda   Tatsuya Hori   
Asian Journal of Animal and Veterinary Advances 9(6) 362-366 2014年 [査読有り]
Superoxide dismutase (SOD) has a key role in protecting1 cells from Reactive Oxygen Species (ROS). Cancer cells produce more ROS involved in proliferation and survival of cancer cells. We, therefore, investigated the percentage of castrated dogs w...
Masanori Kobayashi   Tatsuya Hori   Eiichi Kawakami   
JOURNAL OF VETERINARY MEDICAL SCIENCE 75(9) 1249-1252 2013年9月 [査読有り]
In healthy male dogs, peripheral plasma testosterone (T), prostaglandin E-2 (PGE(2)) and seminal plasma PGE(2) levels were measured before, during and after ejaculation, and semen quality was examined after oral administration of PGE(2). Plasma T ...
The molecular mechanism of muscle degeneration in a lethal muscle disorder Duchene muscular dystrophy (DMD) has not been fully elucidated. The dystrophic dog, a model of DMD, shows a high mortality rate with a marked increase in serum creatine kin...
Duchenne muscular dystrophy (DMD) is a severe and the most prevalent form of muscular dystrophy, characterized by rapid progression of muscle degeneration. Antisense-mediated exon skipping is currently one of the most promising therapeutic options...
Eiichi Kawakami   Tomoko Yagi   Masanori Kobayashi   Tatsuya Hori   
JOURNAL OF VETERINARY MEDICAL SCIENCE 74(2) 201-204 2012年2月 [査読有り]
A Beagle dog (3 years old) that ejaculated high percentages (mean +/- SE: 29.1 +/- 1.2%) of sperm with a knobbed acrosome abnormality and a low number of sperm and that also had a low plasma testosterone (T) level was given 10 subcutaneous injecti...