獣医保健看護学科

研究キーワード

Zoo animal ,Animal model ,Carcinogenesis

研究分野

ライフサイエンス / 腫瘍診断、治療学 /
ライフサイエンス / 実験病理学 / 腫瘍学
ライフサイエンス / 獣医学 / 病理学

委員歴

2020年4月

-

現在

内閣府食品安全委員会動物用医薬品専門調査会専門委員

2019年10月

-

現在

公益財団法人日本獣医学会評議員

2015年12月

-

現在

環境省ライチョウ保護増殖事業死因解明病理検査担当

受賞

1997年1月

第13回日本毒性病理学会年会長賞

1995年1月

第11回日本毒性病理学会年会長賞

論文

<3 456 7 >

Diffuse Pulmonary Meningotheliomatosis withSarcomatous Transformation in a Shiba Dog

Masaki Michishita Aki Fujiwara-Igarashi S Suzuki Hitoshi Hatakeyama Yukino Machida Hisashi Yoshimura Masami Yamamoto Daigo Azakami Kazuhiko Ochiai Toshiyuki Ishiwata Michio Fujita

Journal of Comparative Pathology 171 1-5 2019年8月 [査読有り]

Toxoplasma gondii infection in Amami spiny rat on Amami-Oshima Island, Japan.

Toshihiro Tokiwa Hisashi Yoshimura Sayoko Hiruma Yukie Akahori Ayami Suzuki Keiko Ito Masami Yamamoto Kazunori Ike

International journal for parasitology. Parasites and wildlife 9 244-247 2019年8月 [査読有り]

Expression and Roles of S100A4 in Anaplastic Cells of Canine Mammary Carcinomas.

Hisashi Yoshimura Aya Otsuka Masaki Michishita Masami Yamamoto Minori Ashizawa Manami Zushi Maiko Moriya Daigo Azakami Kazuhiko Ochiai Yoko Matsuda Toshiyuki Ishiwata Shinji Kamiya Kimimasa Takahashi

Veterinary pathology 56(3) 389-398 2019年5月 [査読有り]

S100A4 (metastasin), a member of the S100 protein family, was initially identified in metastatic cells and is well established as a marker of aggressive human cancer. However, expression and roles of S100A4 in canine mammary tumors have not been c...

Reduced expression of the H19 long non-coding RNA inhibits pancreatic cancer metastasis.

Hisashi Yoshimura Yoko Matsuda Masami Yamamoto Masaki Michishita Kimimasa Takahashi Norihiko Sasaki Naoshi Ishikawa Junko Aida Kaiyo Takubo Tomio Arai Toshiyuki Ishiwata

Laboratory investigation; a journal of technical methods and pathology 98(6) 814-824 2018年6月 [査読有り]

H19 is an oncofetal RNA expressed in the developing embryo as well as in bladder, breast, gastric, pancreatic, hepatocellular, and prostate cancers. Recent studies have shown that H19 enhances cancer invasion and metastasis; however, its roles in ...

Established gastric cancer cell lines transplantable into C57BL/6 mice show fibroblast growth factor receptor 4 promotion of tumor growth.

Masami Yamamoto Sachiyo Nomura Akihiro Hosoi Koji Nagaoka Tamaki Iino Tomohiko Yasuda Tomoko Saito Hirokazu Matsushita Eiji Uchida Yasuyuki Seto James R Goldenring Kazuhiko Kakimi Masae Tatematsu Tetsuya Tsukamoto

Cancer science 109(5) 1480-1492 2018年5月 [査読有り]

Previously no mouse gastric cancer cell lines have been available for transplantation into C57BL/6 mice. However, a gastric cancer model in immunocompetent mice would be useful for analyzing putative therapies. N-Methyl-N-nitrosourea (MNU) was giv...