袴田陽二

研究者氏名	袴田陽二

通称等の別名	袴田陽二
所属	日本獣医生命科学大学
部署	獣医学部獣医保健看護学科
職名
学位	獣医学博士(日本獣医畜産大学)
J-Global ID	200901087420386440

研究キーワード

臓器再生 ,神経病理 ,Biotechnology ,Experimental Animal

研究分野

ライフサイエンス / 獣医学 / 動物繁殖学
ライフサイエンス / 実験動物学 /
ライフサイエンス / 神経形態学 /

経歴

2020年4月

現在

慶応義塾大学医学部訪問教授

2012年1月

現在

日本獣医生命科学大学獣医学部獣医保健看護学科教授

2006年4月

2012年1月

日本獣医生命科学大学獣医学部獣医保健看護学科准教授

論文

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Poor outcomes in carriers of the RNF213 variant (p.Arg4810Lys) with pulmonary arterial hypertension.

Takahiro Hiraide Masaharu Kataoka Hisato Suzuki Yuki Aimi Tomohiro Chiba Sarasa Isobe Yoshinori Katsumata Shinichi Goto Kohsuke Kanekura Yoshitake Yamada Hidenori Moriyama Hiroki Kitakata Jin Endo Shinsuke Yuasa Yasumichi Arai Nobuyoshi Hirose Toru Satoh Yoji Hakamata Motoaki Sano Shinobu Gamou Kenjiro Kosaki Keiichi Fukuda

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 39(2) 103-112 2020年2月 [査読有り]

BACKGROUND: A variant of c.14429G>A (p.Arg4810Lys, rs112735431) in the ring finger protein 213 gene (RNF213; NM_001256071.2) has been recently identified as a risk allele for pulmonary arterial hypertension (PAH). PAH can be added as a new member ...

A microsurgical technique for catheter insertion in the rat femoral artery.

Kazuhisa Sugai Yoji Hakamata Tomoyoshi Tamura Masaharu Kataoka Masahiko Fujisawa Motoaki Sano Eiji Kobayashi

Acta cirurgica brasileira 35(10) e202001004 2020年 [査読有り]

PURPOSE: To modify a surgical catheterization method using the bent needle introducer in small animals. METHODS: Eight-week-old male Lewis rats were used in the study. A needle introducer was created by bending a 21G injection needle at 45°. The b...

Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension.

Sarasa Isobe Masaharu Kataoka Jin Endo Hidenori Moriyama Shogo Okazaki Kenji Tsuchihashi Yoshinori Katsumata Tsunehisa Yamamoto Kohsuke Shirakawa Naohiro Yoshida Masayuki Shimoda Tomohiro Chiba Takashi Masuko Yoji Hakamata Eiji Kobayashi Hideyuki Saya Keiichi Fukuda Motoaki Sano

American journal of respiratory cell and molecular biology 61(3) 367-379 2019年9月 [査読有り]

Pulmonary arterial hypertension (PAH) pathogenesis shares similarities with carcinogenesis. One CD44 variant (CD44v) isoform, CD44v8-10, binds to and stabilizes the cystine transporter subunit (xCT), producing reduced glutathione and thereby enhan...

Indigo Naturalis, a Promising Herbal Medicine for Ulcerative Colitis, Can Induce Experimental Pulmonary Arterial Hypertension via Aryl Hydrocarbon Pathway

Yoji Hakamata

Circulation Research 2019年

Therapeutic impact of dietary vitamin D supplementation for preventing right ventricular remodeling and improving survival in pulmonary hypertension

Hiroaki Tanaka Masaharu Kataoka Sarasa Isobe Tsunehisa Yamamoto Kohsuke Shirakawa Jin Endo Toru Satoh Yoji Hakamata Eiji Kobayashi Motoaki Sano Keiichi Fukuda

PLOS ONE 12(7) e0180615 2017年7月 [査読有り]

Background Pulmonary hypertension (PH), caused by elevated pulmonary vascular resistance, leads to right heart failure and ultimately death. Vitamin D deficiency can predispose individuals to hypertension and left ventricular dysfunction; however,...