袴田陽二

研究者氏名	袴田陽二

通称等の別名	袴田陽二
所属	日本獣医生命科学大学
部署	獣医学部獣医保健看護学科
職名
学位	獣医学博士(日本獣医畜産大学)
J-Global ID	200901087420386440

研究キーワード

臓器再生 ,神経病理 ,Biotechnology ,Experimental Animal

研究分野

ライフサイエンス / 獣医学 / 動物繁殖学
ライフサイエンス / 実験動物学 /
ライフサイエンス / 神経形態学 /

経歴

2020年4月

現在

慶応義塾大学医学部訪問教授

2012年1月

現在

日本獣医生命科学大学獣医学部獣医保健看護学科教授

2006年4月

2012年1月

日本獣医生命科学大学獣医学部獣医保健看護学科准教授

論文

<5 678 9 >

A transgenic rat with the human ATTR V30M: A novel tool for analyses of ATTR metabolisms

Mitsuharu Ueda Yukio Ando Yoji Hakamata Masaaki Nakamura Taro Yamashita Konen Obayashi Shingo Himeno Seiichiro Inoue Yuki Sato Takashi Kaneko Nobutoki Takamune Shogo Misumi Shozo Shoji Makoto Uchino Eiji Kobayashi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 352(2) 299-304 2007年1月 [査読有り]

Amyloidogenic transthyretin (ATTR) is the pathogenic protein of familial amyloidotic polyneuropathy (FAP). To establish a tool for analyses of ATTR metabolisms including after liver transplantations, we developed a transgenic rat model expressing ...

Use of sphingosine-1-phosphate 1 receptor agonist, KRP-203, in combination with a subtherapeutic dose of cyclosporine a for rat renal transplantation

Jun Fujishiro Shinji Kudou Satomi Iwai Masafumi Takahashi Yoji Hakamata Miki Kinoshita Satoru Iwanami Shigeru Izawa Tokutaro Yasue Kohei Hashizume Takashi Murakami Eiji Kobayashi

TRANSPLANTATION 82(6) 804-812 2006年9月 [査読有り]

Background. We demonstrate the long-term effectiveness of KRP-203 treatment in combination with a subtherapeutic dose of cyclosporine A (CsA) on rat renal allografts.
Methods. We tested the effect of KRP-203 in combination with CsA using a rat ski...

Severe rejection of rat intestinal grafts overexpressing human histo-blood group A/B transferase

Seiichiro Inoue Kazunori Tahara Jun Fujishiro Wendy Zhou Hideki Ohdan Toshimasa Asahara Kohei Hasnizume Michio Kaneko Yoji Hakamata Koichi Takeuchi Sadahiko Iwamoto Eiji Kobayashi

International Congress Series 1292 13-21 2006年7月 [査読有り]

Background: To test the effect of overexpressed human A/B antigens on rat immunity, we have developed transgenic (Tg) rats with human blood group A/B transferase genes in a previous report. Using these rats whose intestine expressed the A/B antige...

Change from cyclosporine to combination therapy of mycophenolic acid with the new sphingosine-1-phosphate receptor agonist, KRP-203, prevents host nephrotoxicity and transplant vasculopathy in rats

Jun Fujishiro Chihiro Suzuki Shinji Kudou Tokutaro Yasue Yoji Hakamata Masafumi Takahashi Takashi Murakami Kohei Hashizume Eiji Kobayashi

JOURNAL OF HEART AND LUNG TRANSPLANTATION 25(7) 825-833 2006年7月 [査読有り]

Background: Replacement of calcineurin inhibitor (CI) with anti-metabolic agents in transplant patients with CI-induced nephrotoxiciry is performed clinically and improves renal function, but increases the risk of rejection. We investigated whethe...

"Firefly rats" as an organ/cellular source for long-term in vivo bioluminescent imaging

Y Hakamata T Murakami E Kobayashi

TRANSPLANTATION 81(8) 1179-1184 2006年4月 [査読有り]

Background. Transplantation research involving the use of stem cells demands an appropriate in vivo visualization system to monitor cellular fate over an observation period. The new field of in vivo imaging is being developed with fluorescent and ...