This study examined the mechanism of vasorelaxation induced by dimethyl sulfoxide (DMSO) in endothelium-intact and -denuded rat aorta. DMSO (0.1-3%) inhibited phenylephrine (PE, 1 mu mol/l)-induced contraction in a dose-dependent manner. However, ...
Yuta Nagai Takeharu Kaneda Yasuyuki Miyamot Takaomi Nuruki Hidenori Kanda Norimoto Urakawa Kazumasa Shimizu
JOURNAL OF VETERINARY MEDICAL SCIENCE 78(1) 55-59 2016年1月 [査読有り]
To elucidate the dependence of aerobic energy metabolism and utilization of glucose in contraction of urinary bladder smooth muscle, we investigated the changes in the reduced pyridine nucleotide (PNred) fluorescence, representing glycolysis activ...
Takeharu Kaneda Erika Saito Hidenori Kanda Norimoto Urakawa Kazumasa Shimizu
JOURNAL OF VETERINARY MEDICAL SCIENCE 77(10) 1269-1274 2015年10月 [査読有り]
The effects of papaverine on carbachol (CCh) -and high K+-induced contraction in the bovine abomasum were investigated. Papaverine inhibited CCh (1 mu M) -and KCl (65 mM) -induced contractions in a concentration-dependent manner. Forskolin or sodi...
JOURNAL OF VETERINARY MEDICAL SCIENCE 77(1) 15-19 2015年1月 [査読有り]
The effects of various selective phosphodiesterase (PDE) inhibitors on carbachol (CCh)-induced contraction in the bovine abomasum were investigated. Various selective PDE inhibitors, vinpocetine (type 1), erythro-9-(2-hydroxy-3-nonyl) adenine (EHN...
Journal of Smooth Muscle Research 46(1) 17-29 2010年4月 [査読有り]
The effects of various selective phosphodiesterase (PDE) inhibitors on muscle contractility and cyclic nucleotide content in the porcine coronary artery were investigated. Various selective PDE inhibitors, vinpocetine (type 1), erythro-9-(2-hydrox...
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