Yumiko Uno   Shota Kawakami   Kazuhiko Ochiai   Toshinori Omi   
Canine genetics and epidemiology 6(9) 9-9 2019年 [査読有り]
Background: N-glycolylneuraminic acid (Neu5Gc) is synthesized from its precursor N-acetylneuraminic acid (Neu5Ac) by cytidine-5'-monophospho-N acetylneuraminic acid hydroxylase (CMAH), which is encoded by the CMAH gene. Most mammals have both Neu5...
Ochiai K   Azakami D   Morimatsu M   Hirama H   Kawakami S   Nakagawa T   Michishita M   Egusa AS   Sasaki T   Watanabe M   Omi T   
Kawakami S   Ochiai K   Azakami D   Kato Y   Michishita M   Morimatsu M   Ishiguro-Oonuma T   Onozawa E   Watanabe M   Omi T   
The Journal of veterinary medical science 80(1) 85-91 2018年1月 [査読有り]
Gliomas are common intracranial neoplasias in dogs. However, the underlying pathogenic mechanisms remain unclear. In humans, isocitrate dehydrogenase 2 (IDH2) is often mutated in gliomas. Although almost human IDH2 mutations have been identified a...