It is now known that circadian clocks are localized not only in the central pacemaker but also in peripheral organs. An example of a clock-dependent peripheral organ is the ovary of domestic poultry in which ovulation is induced by the positive fe...
The molecular mechanism underlying photoperiodism is not well understood in any organism. Long-day-induced conversion of prohormone T-4 to bioactive T-3 within the mediobasal hypothalamus (MBH) is critical for the photoperiodic regulation of repro...
JOURNAL OF BIOLOGICAL RHYTHMS 22(1) 58-68 2007年2月 [査読有り]
Using the mPer1::luc real-time monitoring technique, the authors observed the bimodal patterns of mPer1 bioluminescence on each side of the SCN, in parallel with maintaining synchronization between the left and right sides of the SCN under an arti...
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 292(1) R568-R572 2007年1月 [査読有り]
Photorefractoriness is the insensitivity of gonadal development to the stimulatory effects of long photoperiods in birds and to the inhibitory effects of short photoperiods in small mammals. Its molecular mechanism remains unknown. Recently, it ha...
T Watanabe   M Kojima   S Tomida   TJ Nakamura   T Yamamura   N Nakao   S Yasuo   T Yoshimura   S Ebihara   
NEUROSCIENCE RESEARCH 54(4) 295-301 2006年4月 [査読有り]
CS mice show unique properties of circadian rhythms: unstable free-running periods and distinct bimodal rhythms (similar to rhythm splitting, but hereafter referred to as bimodal rhythms) under constant darkness. In the present study, we compared ...