Cat's AB blood group system (blood types A, B, and AB) is of major importance in feline transfusion medicine. Type A and type B antigens are Neu5Gc and Neu5Ac, respectively, and the enzyme CMAH participating in the synthesis of Neu5Gc from Neu5Ac ...
European journal of haematology 95(6) 524-31 2015年12月 [査読有り]
Although imatinib has therapeutic activity for certain subsets of patients with mastocytosis, it is not always curative. Here, molecular mechanisms that confer imatinib resistance to neoplastic mast cells were investigated using an imatinib-sensit...
Kato Y   Ochiai K   Michishita M   Azakami D   Nakahira R   Morimatsu M   Ishiguro-Oonuma T   Yoshikawa Y   Kobayashi M   Bonkobara M   Kobayashi M   Takahashi K   Watanabe M   Omi T   
Veterinary journal (London, England : 1997) 206(2) 143-8 2015年11月 [査読有り]
Veterinary journal (London, England : 1997) 205(2) 180-8 2015年8月 [査読有り]
Imatinib inhibits the activity of several tyrosine kinases, including BCR-ABL, KIT and platelet-derived growth factor receptor (PDGFR). Dysregulation of KIT is found in mast cell tumours (MCTs) and KIT is mutated in approximately 30% and 70% of ca...