Biomedical research (Tokyo, Japan) 36(2) 155-8 2015年 [査読有り]
Mutations in the breast cancer susceptibility gene BRCA2 leading to the failure of interactions with the recombinase RAD51 are associated with an increased risk of cancer in humans. This interaction depends on the eight BRC repeat (BRC1-8) sequenc...
Chihiro Udagawa   Naomi Tada   Junzo Asano   Katsumi Ishioka   Kazuhiko Ochiai   Makoto Bonkobara   Shuichi Tsuchida   Toshinori Omi   
BMC research notes 7(1) 904-904 2014年12月 [査読有り]
BACKGROUND: The uncoupling proteins (UCPs) in the mitochondrial inner membrane are members of the mitochondrial anion carrier protein family that play an important role in energy homeostasis. Genetic association studies have shown that human UCP2 ...
The Journal of veterinary medical science 76(12) 1641-5 2014年12月 [査読有り]
Apoptosis inhibitor of macrophage (AIM) plays roles in survival of macrophages. In this study, we cloned canine AIM cDNA and observed its transcriptional expression levels in various tissues. The coding sequence of canine AIM was 1,023 bp encoding...
Veterinary journal (London, England : 1997) 198(3) 577-82 2013年12月 [査読有り]
Canine malignant melanomas are highly aggressive and fatal neoplasms. In the present report, 21 drugs that target specific signalling pathways were screened for their growth inhibitory activity on three canine malignant melanoma cell lines. The pr...
Legal medicine (Tokyo, Japan) 15(6) 303-9 2013年11月 [査読有り]
To develop DNA markers for forensic analysis, we examined the hypervariable region 1 (HVR1) sequences of 447 pure-bred domestic dogs (Canis lupus familiaris) that had been bred and raised in Japan. HVR1 is a 660-bp stretch of mitochondrial (mt) DN...