JOURNAL OF IMMUNOLOGY 171(2) 783-794 2003年7月 [査読有り]
We found a tight correlation among the levels of H4/inducible costimulator (ICOS) expression, IL-4 production, and GATA-3 induction, using activated CD4(+) T cells obtained from six different murine strains. BALB/c-activated CD4(+) T cells express...
INTERNATIONAL IMMUNOLOGY 14(6) 555-566 2002年6月 [査読有り]
We examined the co-stimulatory activity of H4/ICOS on murine activated CD4(+) T cells and found that the cross-linking of H4/ICOS enhanced their proliferation, in addition to raising IFN-gamma, IL-4 and IL-10 production to levels comparable to tho...
Journal of Infection and Chemotherapy 8(1) 111-114 2002年 [査読有り]
The behavior of Vβ2+ T cells reactive with the pathogenic superantigen toxic shock syndrome toxin-1 (TSST-1) was examined in 12 patients with neonatal TSS-like exanthematous disease (NTED). In 8 patients, the percentage of Vβ2+ T cells in peripher...
JOURNAL OF BIOLOGICAL CHEMISTRY 276(11) 8550-8556 2001年3月 [査読有り]
Stimulation of B cell antigen receptor (BCR) may induce proliferation, differentiation, or apoptosis, depending upon the maturational stage of the cell and the presence or absence of signals transmitted via coreceptors. One such signal is delivere...
M Ogimoto   Y Arimura   T Katagiri   K Mitomo   Woodgett, JR   AR Nebreda   K Mizuno   H Yakura   
FEBS LETTERS 490(1-2) 97-101 2001年2月 [査読有り]
In this study, we examined the contribution made by CD45 to B cell antigen receptor (BCR)-induced activation of mitogen-activated protein kinase (MAPK) family members, We found that CD45 negatively regulated BCR-induced c-Jun NH2-terminal kinase (...