Journal of Pharmacological Sciences 136(1) 26-30 2018年1月 [査読有り]
Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica. In this study, the effect of CGA-induced relaxation on carbachol (CCh)-induced contraction of mouse urinary bladder was investigated. CGA (30–300...
JOURNAL OF VETERINARY MEDICAL SCIENCE 79(4) 719-725 2017年4月 [査読有り]
Canine prostate cancer (cPCa) is an untreatable malignant neoplasm resulting in local tissue invasion and distant metastasis. MicroRNAs (miRs) are small non-coding RNAs that function as oncogenes or tumor suppressors. The purpose of this study was...
JOURNAL OF VETERINARY MEDICAL SCIENCE 79(3) 593-601 2017年3月 [査読有り]
Recent studies have shown that phloridzin, an inhibitor of sodium glucose cotransporter (SGLT), strongly decreases high K+-induced contraction in phasic muscle, such as tenia coil, but slightly affects tonic muscle, such as trachea. In this study,...
JOURNAL OF VETERINARY MEDICAL SCIENCE 78(11) 1673-1676 2016年11月 [査読有り]
Eyes are supplied O-2 through the cornea and vessels of the retina and iris, which are tissues characterized by aerobic metabolism. Meanwhile, there are no reports on the association between iris sphincter contraction and aerobic metabolism. In th...
Yuta Nagai Takeharu Kaneda Yasuyuki Miyamot Takaomi Nuruki Hidenori Kanda Norimoto Urakawa Kazumasa Shimizu
JOURNAL OF VETERINARY MEDICAL SCIENCE 78(1) 55-59 2016年1月 [査読有り]
To elucidate the dependence of aerobic energy metabolism and utilization of glucose in contraction of urinary bladder smooth muscle, we investigated the changes in the reduced pyridine nucleotide (PNred) fluorescence, representing glycolysis activ...
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