T Kaneda   K Shimizu   S Nakajyo   N Urakawa   
JAPANESE JOURNAL OF PHARMACOLOGY 75(1) 77-85 1997年9月 [査読有り]
The effects of various selective phosphodiesterase (PDE) inhibitors on muscle contractility in guinea pig ileal longitudinal smooth muscle were investigated. 1) 3-Isobutyl-1-methyl xanthine (IBMX) or zaprinast markedly inhibited the high K+- or ca...
T KANEDA   K SHIMIZU   S NAKAJYO   N URAKAWA   
JAPANESE JOURNAL OF PHARMACOLOGY 69(3) 195-204 1995年11月 [査読有り]
Effects of phorbol ester, 12-deoxyphorbol 13-isobutyrate (DPB), on muscle tension and cytosolic Ca2+ ([Ca2+](i)) level was investigated in rat anococcygeus muscle in comparison with other smooth muscles. 1) DPB (10(-6) M) induced a large contracti...
Journal of Smooth Muscle Research 31(4) 163-173 1995年 [査読有り]
A contractile propertiy of phenylephrine (PE), α1 agonist, on rat anococcygeus muscle was compared with that on rat aorta by simultaneously measuring changes in intracellular Ca2+ ([Ca2+] 1 level and muscle tension.(1) PE (0.1~30, μ M) and high K+...