Hiroshi M Ueno   Touko Sato   Satoshi Higurashi   Hiroyuki Tazaki   Yasuhiro Toba   
Current developments in nutrition 6(6) nzac093 2022年6月 [査読有り]
Background: Maternal diet and sociodemographic factors influence xanthophyll concentration and composition in human milk. However, the importance of dietary patterns regarding the intake of fruits, vegetables, and xanthophylls remains unclear. Obj...
BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used to reduce hyperglycemia. The present study investigated the effects of a SGLT2 inhibitor, empagliflozin, on hyperglycemia in a novel rat model of non-obesity type 2 diab...
The Journal of veterinary medical science 82(4) 446-451 2020年4月 [査読有り]
Information regarding the pharmacokinetics of oral sildenafil in dogs with pulmonary hypertension is limited. In this study, we examined the pharmacokinetics of oral sildenafil in a canine model of chronic embolic pulmonary hypertension (CEPH). Th...
The Journal of veterinary medical science 81(9) 1238-1248 2019年9月 [査読有り]
Cancer consists of heterogeneous cells that contain a small population of cells that possess stem cell properties; these cells, referred to as cancer stem cells (CSCs) or tumor-initiating cells, are involved in tumor progression and metastasis. Us...