氏家誠

研究者氏名	氏家誠

所属	日本獣医生命科学大学
部署	獣医学部獣医学科獣医感染症学研究室
職名	准教授
学位	博士（医学）(名古屋市立大学)
J-Global ID	201601020286651431

研究分野

ライフサイエンス / ウイルス学 /

論文

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Oseltamivir-resistant influenza viruses A (H1N1) during 2007-2009 influenza seasons, Japan.

Makoto Ujike Kozue Shimabukuro Kiku Mochizuki Masatsugu Obuchi Tsutomu Kageyama Masayuki Shirakura Noriko Kishida Kazuyo Yamashita Hiroshi Horikawa Yumiko Kato Nobuyuki Fujita Masato Tashiro Takato Odagiri

Emerging infectious diseases 16(6) 926-35 2010年6月 [査読有り]

To monitor oseltamivir-resistant influenza viruses A (H1N1) (ORVs) with H275Y in neuraminidase (NA) in Japan during 2 influenza seasons, we analyzed 3,216 clinical samples by NA sequencing and/or NA inhibition assay. The total frequency of ORVs wa...

A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir.

Yoko Matsuzaki Katsumi Mizuta Yoko Aoki Asuka Suto Chieko Abiko Kanako Sanjoh Kanetsu Sugawara Emi Takashita Tsutomu Itagaki Yuriko Katsushima Makoto Ujike Masatsugu Obuchi Takato Odagiri Masato Tashiro

Virology journal 7 53-53 2010年3月 [査読有り]

BACKGROUND: Oseltamivir is the preferred antiviral drug for influenza, but oseltamivir-resistant A(H1N1) viruses have circulated worldwide since the 2007-2008 influenza season. We aimed to determine the rate of oseltamivir resistance among A(H1N1)...

Isolation of oseltamivir-resistant influenza A/H1N1 virus of different origins in Yokohama City, Japan, during the 2007-2008 influenza season.

Chiharu Kawakami Masatsugu Obuchi Miwako Saikusa Yuzo Noguchi Makoto Ujike Takato Odagiri Mami Iwata Takahiro Toyozawa Masato Tashiro

Japanese journal of infectious diseases 62(1) 83-6 2009年1月 [査読有り]

Heptad repeat-derived peptides block protease-mediated direct entry from the cell surface of severe acute respiratory syndrome coronavirus but not entry via the endosomal pathway.

Makoto Ujike Hiroki Nishikawa Akira Otaka Naoki Yamamoto Norio Yamamoto Masao Matsuoka Eiichi Kodama Nobutaka Fujii Fumihiro Taguchi

Journal of virology 82(1) 588-92 2008年1月 [査読有り]

The peptides derived from the heptad repeat (HRP) of severe acute respiratory syndrome coronavirus (SCoV) spike protein (sHRPs) are known to inhibit SCoV infection, yet their efficacies are fairly low. Recently our research showed that some protea...

A point mutation at the C terminus of the cytoplasmic domain of influenza B virus haemagglutinin inhibits syncytium formation.

Makoto Ujike Katsuhisa Nakajima Eri Nobusawa

The Journal of general virology 87(Pt 6) 1669-1676 2006年6月 [査読有り]

The C-terminal sequence of the cytoplasmic tail (CT) of influenza B haemagglutinin (BHA) consists of strictly conserved, hydrophobic amino acids, and the endmost C-terminal amino acid of the CT is Leu. To elucidate the role of this amino acid in t...