Journal of Bone Oncology 34 100430-100430 2022年6月 [査読有り]
Background: Chondrosarcoma is a common form of malignant bone tumor with limited treatment options. Approximately half of chondrosarcomas harbor gain-of-function mutations in isocitrate dehydrogenase (IDH), and mutant IDH produces 2-hydroxyglutara...
Journal of Veterinary Medical Science 2022年 [査読有り]
We examined the clinical signs and necropsy findings of a mountain hawk-eagle (Nisaetus nipalensis) that died during rehabilitation. The bird was rescued and treated for open fracture of the right forearm. During rehabilitation, the bird could not...
Journal of Feline Medicine and Surgery Open Reports 8(1) 205511692210742-205511692210742 2022年1月 [査読有り]
<sec><title>Case summary</title> A 4-year-old castrated male domestic shorthair cat with a continuous cough was brought to a private veterinary clinic for detailed examination. Radiography of the thoracic cavity revealed a severe radiopaque region...
Proceedings of the National Academy of Sciences 118(43) e2103658118-e2103658118 2021年10月 [査読有り]
Although it is held that proinflammatory changes precede the onset of breast cancer, the underlying mechanisms remain obscure. Here, we demonstrate that FRS2β, an adaptor protein expressed in a small subset of epithelial cells, triggers the proinf...
Journal of Comparative Pathology 188 21-25 2021年10月 [査読有り]
A 20-year-old Dutch Warmblood gelding was referred with clinical signs of anorexia, weight loss, intermittent fever, cough, subcutaneous oedema and exercise intolerance. Haematological examination revealed the presence of blast cells, decreased ly...