Koji Kubota   Mana Okasaka   Asami Kano   Sadaki Takata   
SKIN RESEARCH AND TECHNOLOGY 27(2) 241-248 2021年3月 [査読有り]
Background/purpose Detailed information on the mechanism by which surfactants affect the skin barrier function is still scarce. We investigated the contribution of protein denaturation to the effect of surfactants on barrier function. Methods The ...
Anionic surfactants are commonly used as detergents and emulsifiers. However, these compounds are potent skin irritants. In this study, we evaluated the effect of the alkyl structure of anionic surfactants on the skin barrier function using the tr...
Elderly people show a decline in the ability to decode facial expressions, but also experience age-related facial structure changes that may render their facial expressions harder to decode. However, to date there is no empirical evidence to suppo...
Mana Okasaka   Koji Kubota   Emi Yamasaki   Jianzhong Yang   Sadaki Takata   
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 24(1) 99-104 2019年1月 [査読有り]
Anionic surfactants are often used for cleaning and pharmaceutical purposes because of their strong surfactancy and foaming property. However, they are rarely ingested orally, the skin is a part of the human body most affected by surfactants. Barr...
In most cases, a meal cannot be finished with a single bite and sip. During eating and drinking, consumers receive dynamic food perceptions from sensory attributes in foods. Thus, we performed multi-sip time-intensity (TI) evaluation of sensory at...