Mitochondrial succinate dehydrogenase (SDH) is localized to the inner mitochondrial membrane and is responsible for the redox of succinic acid. SDH is a tetrameric iron-sulfur flavoprotein of the tricarboxylic acid cycle and respiratory chain. The...
Mayumi Chiba Chikako Yokoyama Mai Okada Hisashi Hisatomi
TUMOR BIOLOGY 35(12) 12689-12693 2014年12月 [査読有り]
Three-dimensional (3D) cell culture reflects many of the important properties of solid tumors, such as the inadequate diffusion of oxygen that results in hypoxia. To understand the mitochondrial states in cancer, we performed comparisons of the le...
Background: Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) are myeloproliferative neoplasms (MPNs) characterized in most cases by a unique somatic mutation, JAK2 V617F. Recent studies revealed that JAK2 V61...
EXPERIMENTAL AND THERAPEUTIC MEDICINE 2(1) 85-87 2011年1月 [査読有り]
Nerve growth factor (NGF) normally induces the differentiation of PCl2 cells into a neuron-like phenotype. In this study, we found that exposure of PC12 cells to a temperature of 42 degrees C for 24 h significantly decreased NGF-induced neurite el...
経済学部 教員紹介
理工学部 教員紹介
法科大学院 教員紹介（リンク）