Hikaru Matsushima   Makoto Hirano   Yukishige Ito   Kiichiro Totani   
CHEMBIOCHEM 14(6) 753-758 2013年4月 [査読有り]
Compared with in vitro conditions, the intracellular environment is highly crowded with biomolecules; this has numerous effects on protein functions, including enzymatic activity. We examined the effects of macromolecular crowding on glycan proces...
Glycoprotein oligosaccharides function as tags for protein quality control in the endoplasmic reticulum (ER). Since most of proteins are glycosylated and function only after they are properly folded, glycoprotein glycan profiles in the ER might be...