Md. Ashad Alam   Osamu Komori   Hong-Wen Deng   Vince D. Calhoun   Yu-Ping Wang   
Journal of Bioinformatics and Computational Biology 17(04) 1950028-1950028 2019年8月
The kernel canonical correlation analysis based U-statistic (KCCU) is being used to detect nonlinear gene–gene co-associations. Estimating the variance of the KCCU is however computationally intensive. In addition, the kernel canonical correlation...
Pancreatic ductal adenocarcinoma (PDAC) is the most life‐threating disease among all digestive system malignancies. We developed a blood mRNA PDAC screening system using real‐time detection PCR to detect the expression of 56 genes, to discriminate...
Seungchul Baek   Osamu Komori   Yanyuan Ma   
Scandinavian Journal of Statistics 45(3) 806-846 2018年4月
Abstract
In the classical discriminant analysis, when two multivariate normal distributions with equal variance–covariance matrices are assumed for two groups, the classical linear discriminant function is optimal with respect to maximizing the s...