Transplantation technologies of pancreatic islets as well as stem cell-derived pancreatic beta cells encapsulated in hydrogel for the induction of immunoprotection could advance to treat type 1 diabetes mellitus, if the hydrogel transplants acquir...
Shogo Nagata Fumisato Ozawa Minghao Nie Shoji Takeuchi
PloS one 15(6) e0234441 2020年6月 [査読有り]
Human iPSC-derived hepatocytes hold great promise as a cell source for cell therapy and drug screening. However, the culture method for highly-quantified hepatocytes has not yet been established. Herein, we have developed an encapsulation and 3D c...
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 1187-1188 2020年 [査読有り]
This paper describes probiotic microfibers for oral delivery to reestablished healthy microbiome (Fig. 1). Recent discoveries in biology and microbiology have gained much importance of the gastrointestinal microbiome in regulating human health and...
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 2019-January 597-598 2019年1月 [査読有り]
In this paper, we demonstrate that hepatocytes derived from human pluripotent stem cells (iPSCs) could promote their cell characteristics in cell-laden core-shell microfiber. The iPSC-hepatocytes are expected as cell source for regenerative medici...
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 2019-January 586-587 2019年1月 [査読有り]
We developed a continuous glucose monitoring (CGM) system for the monitoring of 3D tissue in vitro using a perfusable device. The system consists of perfusable cell culture unit and CGM unit that has a fluorescent-based glucose responsive hydrogel...
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