Fujii T   Segawa H   Hanazaki A   Nishiguchi S   Minoshima S   Ohi A   Tominaga R   Sasaki S   Tanifuji K   Koike M   Arima Y   Shiozaki Y   Kaneko I   Ito M   Tatsumi S   Miyamoto KI   
Clinical and experimental nephrology 23(7) 898-907 Mar 2019 [Refereed]
BACKGROUND: Injection of parathyroid hormone (PTH) rapidly stimulates renal Pi excretion, in part by downregulating NaPi-IIa (Npt2a/SLC34A1) and NaPi-IIc (Npt2c/SLC34A3) transporters. The mechanisms underlying the effects of PTH on NaPi-IIc are no...
Ikuta K   Segawa H   Hanazaki A   Fujii T   Kaneko I   Shiozaki Y   Tatsumi S   Ishikawa Y   Miyamoto KI   
Pflugers Archiv : European journal of physiology 471(1) 123-136 Jan 2019 [Refereed]
Inorganic phosphate (Pi) secretion from the salivary glands and dietary Pi are key Pi sources. The regulatory mechanisms of Pi homeostasis in the salivary glands are unknown. We investigated how salivary Pi concentrations are regulated by dietary ...
Fujii T   Shiozaki Y   Segawa H   Nishiguchi S   Hanazaki A   Noguchi M   Kirino R   Sasaki S   Tanifuji K   Koike M   Yokoyama M   Arima Y   Kaneko I   Tatsumi S   Ito M   Miyamoto KI   
Clinical and experimental nephrology 23(3) 313-324 Oct 2018 [Refereed]
BACKGROUND: The role of Na+-dependent inorganic phosphate (Pi) transporters in the human kidney is not fully clarified. Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is caused by loss-of-function mutations in the IIc Na+-dependent...