Yasuyuki Sawada Takeshi Nomura Boris Martinac Masahiro Sokabe
Frontiers in chemistry 11 1175443-1175443 Jun 2023 [Refereed]
The bacterial mechanosensitive channel of large conductance MscL is activated exclusively by increased tension in the membrane bilayer. Despite many proposed models for MscL opening, its precise mechano-gating mechanism, particularly how the recei...
Ibrahim M Almanjahie Ramzan Nazim Khan Robin K Milne Takeshi Nomura Boris Martinac
European biophysics journal : EBJ 48(4) 383-393 May 2019 [Refereed]
Ion channel data recorded using the patch clamp technique are low-pass filtered to remove high-frequency noise. Almanjahie et al. (Eur Biophys J 44:545-556, 2015) based statistical analysis of such data on a hidden Markov model (HMM) with a moving...
Tension in cell membranes is closely related to various cellular events, including cell movement and morphogenesis. Therefore, modulation of membrane tension can be a new approach for manipulating cellular events. Here, we show that an amphipathic...
Navid Bavi Adam D. Martinac D. Marien Cortes Omid Bavi Pietro Ridone Takeshi Nomura Adam P. Hill Boris Martinac Eduardo Perozo
SCIENTIFIC REPORTS 7(1) 17229-17229 Dec 2017 [Refereed]
The large conductance mechanosensitive channel (MscL), acts as an osmoprotective emergency valve in bacteria by opening a large, water- filled pore in response to changes in membrane tension. In its closed configuration, the last 36 residues at th...
The detailed single-channel gating kinetics of mouse pannexin 1 (mPanx1) remains unknown, although mPanx1 is reported to be a voltage-activated anion-selective channel. We investigated characteristics of single-channel conductances and opening and...
Charles G. Cranfield, Anna Kloda, Yury A. Nikolaev, Adam D. Martinac, Pietro Ridone, Navid Bavi, Omid Bavi, Evgeny Petrov, Andrew R. Battle, Takeshi Nomura, Paul R. Rohde, Yoshitaka Nakayama, Kadla R. Rosholm, Charles D. Cox, Matthew A. Baker and Boris Martinac(Part:Contributor)
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