The bacterial mechanosensitive channel MscS protects the bacteria from rupture on hypoosmotic shock. MscS is composed of a transmembrane domain with an ion permeation pore and a large cytoplasmic vestibule that undergoes significant conformational...
The mechanosensitive channel of small conductance (MscS) is a bacterial mechanosensitive channel that opens in response to rapid hypoosmotic stress. Since MscS can be opened solely by membrane stretch without help from any accessory protein, the l...
MscL is a bacterial mechanosensitive channel that is activated directly by membrane stretch. Although the gene has been cloned and the crystal structure of the closed channel has been defined, how membrane tension causes conformational changes in ...
The bacterial MscL (mechanosensitive channel of large conductance) is one of the best studied Mechanosensitive (MS) channels owing to its resolved 3D structure by X-ray crystallography. In addition MscL is known to be activated solely by tension i...
Charles G. Cranfield, Anna Kloda, Yury A. Nikolaev, Adam D. Martinac, Pietro Ridone, Navid Bavi, Omid Bavi, Evgeny Petrov, Andrew R. Battle, Takeshi Nomura, Paul R. Rohde, Yoshitaka Nakayama, Kadla R. Rosholm, Charles D. Cox, Matthew A. Baker and Boris Martinac(担当:分担執筆)