Max E. Harner Ann-Katrin Unger Willie J. C. Geerts Muriel Mari Toshiaki Izawa Maria Stenger Stefan Geimer Fulvio Reggiori Benedikt Westermann Walter Neupert
ELIFE 5(e18853) 2016年11月 [査読有り]
Metabolic function and architecture of mitochondria are intimately linked. More than 60 years ago, cristae were discovered as characteristic elements of mitochondria that harbor the protein complexes of oxidative phosphorylation, but how cristae a...
Since messenger RNAs without a stop codon (nonstop mRNAs) for organelle-targeted proteins and their translation products (nonstop proteins) generate clogged translocon channels as well as stalled ribosomes, cells have mechanisms to degrade nonstop...
The mechanisms responsible for active DNA demethylation remain elusive in Metazoa. A previous study that utilized zebrafish embryos provided a potent mechanism for active demethylation in which three proteins, AID, MBD4, and GADD45 are involved. W...
Max Emanuel Harner Ann-Katrin Unger Toshiaki Izawa Dirk M. Walther Cagakan Oezbalci Stefan Geimer Fulvio Reggiori Britta Bruegger Matthias Mann Benedikt Westermann Walter Neupert
ELIFE 3(e01684) 2014年4月 [査読有り]
Structure and function of mitochondria are intimately linked. In a search for components that participate in building the elaborate architecture of this complex organelle we have identified Aim24, an inner membrane protein. Aim24 interacts with th...
Age-related changes in DNA methylation have been demonstrated in mammals, but it remains unclear as to the generality of this phenomenon in vertebrates, which is a criterion for the fundamental cause of senescence. Here we showed that the zebrafis...
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理学研究科