Introduction: Earlier we have demonstrated a prothrombotic state in spontaneously atherogenic rodents kept on Western-style high fat diet. The aim of the present study was to investigate the cellular mechanism of such prothrombotic state. Material...
The aim of the present study was to investigate the effect of a NO donor (GSNO) and a plasma kallikrein inhibitor (PKSI-527) alone and in combination on global haemostatic status. A new in vitro test was employed which allows the measurement of bo...
T. Yamashita   A. Sato   H. Ikarugi   A. Inoue   K. Kitamari   H. Ishii   J. Yamamoto   
Thrombosis Research 116(2) 127-131 2005年 [査読有り]
Background: Although incidence of arterial thrombotic events increases with advancing age, the mechanism of such increased risk is poorly understood. There is also a gender difference
coronary heart disease is more common in men than women. The a...