One of the aims of synthetic biology is bottom-up construction of reconstituted human cells for medical uses. To that end, we generated giant unilamellar vesicles (GUVs) that contained a HeLa cell extract, which comprises a cell-free protein synth...
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY 83(2) 252-258 2017年8月 [査読有り]
A high proton-conducting P2O5-SiO2 nanoporous glass rod was prepared via sol-gel technique, and its tip was sharpened by a meniscus-etching method. The glass rod shows proton conductivity of 1 x 10(-3) at room temperature after absorption of water...
Protein misfolding and aggregation is one of the major causes of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Huntington's disease. So far protein aggregation related to these diseases has been studied using ani...
Journal of Structural and Functional Genomics 17(1) 33-38 2016年3月 [査読有り]
Tight control of protein synthesis is necessary for cells to respond and adapt to environmental changes rapidly. Eukaryotic translation initiation factor (eIF) 2B, the guanine nucleotide exchange factor for eIF2, is a key target of translation con...