Ryusuke Takechi   Helman Alfonso   Amy Harrison   Naoko Hiramatsu   Akari Ishisaka   Akira Tanaka   La'Belle Tan   Andy H Lee   
Asia Pacific journal of clinical nutrition 27(2) 460-465 2018年 [査読有り]
BACKGROUND AND OBJECTIVES: Despite the demonstrated protective effects of green tea and coffee intake against several chronic diseases, finding between studies have not been consistent. One potential reason of this discrepancy is the imprecision i...
Molecular nutrition & food research 61(9) 2017年9月 [査読有り]
SCOPE: Manuka honey, which shows strong nonperoxide-dependent antibacterial activity, contains unique components, such as methyl syringate 4-O-β-D-gentiobioside (leptosperin) and its aglycone, methyl syringate (MSYR). To determine the potential fo...
Naoko Suga   Akira Murakami   Yoshimasa Nakamura   Akari Ishisaka   Noritoshi Kitamoto   Mikiko Ito   Yoji Kato   
Free radical research 51(5) 545-553 2017年5月 [査読有り]
Serotonin (5-hydroxytryptamine) is a putative substrate for myeloperoxidase, which may convert it into the reactive quinone tryptamine-4,5-dione (TD). In this study, we found that the viability of human SH-SY5Y neuroblastoma cells treated with 25 ...
Free radical biology & medicine 101 500-510 2016年12月 [査読有り]
The modification of 5-hydroxyindoleacetic acid (5HIAA) by myeloperoxidase with a xanthine oxidase system was investigated by chromatographic analyses. Two major products were identified as a dimer and quinone (indoleacetate dione) of 5HIAA. The fo...
Bioscience, biotechnology, and biochemistry 80(10) 2007-13 2016年10月 [査読有り]
Lipid peroxidation products react with cellular molecules, such as DNA bases, to form covalent adducts, which are associated with aging and disease processes. Since lipid peroxidation is a complex process and occurs in multiple stages, there might...