Ryusuke Takechi Helman Alfonso Amy Harrison Naoko Hiramatsu Akari Ishisaka Akira Tanaka La'Belle Tan Andy H Lee
Asia Pacific journal of clinical nutrition 27(2) 460-465 2018年
BACKGROUND AND OBJECTIVES: Despite the demonstrated protective effects of green tea and coffee intake against several chronic diseases, finding between studies have not been consistent. One potential reason of this discrepancy is the imprecision i...
SCOPE: Manuka honey, which shows strong nonperoxide-dependent antibacterial activity, contains unique components, such as methyl syringate 4-O-β-D-gentiobioside (leptosperin) and its aglycone, methyl syringate (MSYR). To determine the potential fo...
Naoko Suga Akira Murakami Yoshimasa Nakamura Akari Ishisaka Noritoshi Kitamoto Mikiko Ito Yoji Kato
Free radical research 51(5) 545-553 2017年5月
Serotonin (5-hydroxytryptamine) is a putative substrate for myeloperoxidase, which may convert it into the reactive quinone tryptamine-4,5-dione (TD). In this study, we found that the viability of human SH-SY5Y neuroblastoma cells treated with 25 ...
Yoji Kato Kota Oki Naoko Suga Shigeki Ono Akari Ishisaka Yoko Miura Satoshi Kanazawa Michitaka Naito Noritoshi Kitamoto Anthony J Kettle
Free radical biology & medicine 101 500-510 2016年12月
The modification of 5-hydroxyindoleacetic acid (5HIAA) by myeloperoxidase with a xanthine oxidase system was investigated by chromatographic analyses. Two major products were identified as a dimer and quinone (indoleacetate dione) of 5HIAA. The fo...
Bioscience, biotechnology, and biochemistry 80(10) 2007-13 2016年10月
Lipid peroxidation products react with cellular molecules, such as DNA bases, to form covalent adducts, which are associated with aging and disease processes. Since lipid peroxidation is a complex process and occurs in multiple stages, there might...
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