MOLECULAR BIOLOGY OF THE CELL 26(10) 1957-1970 2015年5月 [査読有り]
Precise wiring patterns of axons are among the remarkable features of neuronal circuit formation, and establishment of the proper neuronal network requires control of outgrowth, branching, and guidance of axons. R-Ras is a Ras-family small GTPase ...
Semaphorins: A Diversity of Emerging Physiological and Pathological Activities 1-18 2015年1月 [査読有り]
Semaphorins, which are a large family of secreted and membrane-bound molecules, were initially identified as neuronal axon-guidance signaling molecules but are now known as important key regulators for cell adhesion and motility in a wide range of...
Vance P. Lemmon   Adam R. Ferguson   Phillip G. Popovich   Xiao-Ming Xu   Diane M. Snow   Michihiro Igarashi   Christine E. Beattie   John L. Bixby   
JOURNAL OF NEUROTRAUMA 31(15) 1354-1361 2014年8月 [査読有り]
The lack of reproducibility in many areas of experimental science has a number of causes, including a lack of transparency and precision in the description of experimental approaches. This has far-reaching consequences, including wasted resources ...
MOLECULAR BIOLOGY OF THE CELL 23(14) 2793-2804 2012年7月 [査読有り]
Regulation of axon growth, guidance, and branching is essential for constructing a correct neuronal network. R-Ras, a Ras-family small GTPase, has essential roles in axon formation and guidance. During axon formation, R-Ras activates a series of p...
JOURNAL OF NEUROSCIENCE 32(24) 8293-8305 2012年6月 [査読有り]
Semaphorins have been identified as repulsive guidance molecules in the developing nervous system. We recently reported that the semaphorin 4D (Sema4D) receptor Plexin-B1 induces repulsion in axon and dendrites by functioning as a GTPase-activatin...