JOURNAL OF BIOLOGICAL CHEMISTRY 282(1) 303-318 2007年1月 [査読有り]
The initial event in establishing a polarized neuron is the specification of a single axon. Spatially regulated glycogen synthase kinase-3 beta (GSK-3 beta) activity is critical for specifying axon-dendrite fate; however, the upstream signaling of...
Y Ito   Oinuma, I   H Katoh   K Kaibuchi   M Negishi   
EMBO REPORTS 7(7) 704-709 2006年7月 [査読有り]
Plexins are receptors for the axonal guidance molecules known as semaphorins, and the semaphorin 4D (Sema4D) receptor plexin-B1 induces repulsive responses by functioning as an R-Ras GTPase-activating protein (GAP). Here we characterized the downs...
Oinuma, I   H Katoh   M Negishi   
JOURNAL OF CELL BIOLOGY 173(4) 601-613 2006年5月 [査読有り]
Plexins are cell surface receptors for semaphorins and regulate cell migration in many cell types. We recently reported that the semaphorin 4D (Sema4D) receptor Plexin-B1 functions as a GTPase-activating protein ( GAP) for R-Ras, a member of Ras f...
Axon guidance represents an important step in the formation of neuronal networks. Axons are guided by various guidance factors, such as semaphorins, slits, ephrins, and netrins. Plexins are cell surface receptors for the repulsive molecules of the...
M Negishi   Oinuma, I   H Katoh   
CELLULAR AND MOLECULAR LIFE SCIENCES 62(12) 1363-1371 2005年6月 [査読有り]
Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as semaphorins, ephrins and netrin. Plexins function as receptors for the repulsive axonal guidance molecules semaph...