Kohei Hatta   Andreas W. Püschel   Charles B. Kimmel   
Proceedings of the National Academy of Sciences of the United States of America 91(6) 2061-2065 1994年3月 [査読有り]
In all vertebrates the brain develops from the enlarged anterior part of the neural plate. However, in the zebrafish mutant cyclops, the girth of the central nervous system (CNS) is nearly uniform along its length. Changes in expression patterns o...
Islet‐1 (Isl‐1) is a LIM domain/homeodomain‐type transcription regulator that has been originally identified as an insulin gene enhancer binding protein. Isl‐1 is also expressed by subsets of neurons in the central nervous system of rat and chick ...
To determine the role of the floor plate (FP) in CNS development, I have used labeling techniques, including immunolabeling, to analyze cyclops mutant embryos, which lack the FP. Except for the anterior brain, the mutant phenotype is almost exclus...
Charles B. Kimmel   Thomas F. Schilling   Kohei Hatta   
Current Topics in Developmental Biology 25(C) 77-110 1991年1月 [査読有り]
This chapter discusses the patterning of body segments of the zebrafish embryo. Descriptive studies in zebrafish have provided exceptionally clear information, often at the level of individual cells, about the structure, extent in the body, and de...
Kohei Hatta   Charles B. Kimmel   Robert K. Ho   Charline Walker   
Nature 350(6316) 339-341 1991年 [査読有り]
THE floor plate is a set of epithelial cells present in the ventral midline of the neural tube in vertebrates1 that seems to have an important role in the developmental patterning2 of central nervous system fibre pathways3,4, and arrangements of s...