Takeshi Yokoyama   Kodai Machida   Wakana Iwasaki   Tomoaki Shigeta   Madoka Nishimoto   Mari Takahashi   Ayako Sakamoto   Mayumi Yonemochi   Yoshie Harada   Hideki Shigematsu   Mikako Shirouzu   Hisashi Tadakuma   Hiroaki Imataka   Takuhiro Ito   
Molecular cell 74(6) 1205-1214 2019年6月 [査読有り]
Translation initiation of hepatitis C virus (HCV) genomic RNA is induced by an internal ribosome entry site (IRES). Our cryoelectron microscopy (cryo-EM) analysis revealed that the HCV IRES binds to the solvent side of the 40S platform of the cap-...