DEVELOPMENT GROWTH & DIFFERENTIATION 52(2) 235-244 2010年2月 [査読有り]
Primordial germ cells (PGCs) in Xenopus embryo are specified in the endodermal cell mass and migrate dorsally toward the future gonads. The role of the signal mediated by Notch and Suppressor of Hairless [Su(H)] was analyzed on the migrating PGCs ...
Igor Adameyko Francois Lallemend Jorge B. Aquino Jorge A. Pereira Piotr Topilko Thomas Mueller Nicolas Fritz Anna Beljajeva Makoto Mochii Isabel Liste Dmitry Usoskin Ueli Suter Carmen Birchmeier Patrik Ernfors
CELL 139(2) 366-379 2009年10月 [査読有り]
Current opinion holds that pigment cells, melanocytes, are derived from neural crest cells produced at the dorsal neural tube and that migrate under the epidermis to populate all parts of the skin. Here, we identify growing nerves projecting throu...
Electroporation and Sonoporation in Developmental Biology 239-247 2009年 [査読有り]
Xenopus laevis is a model system widely used to investigate embryogenesis, metamorphosis, and regeneration. The tail of the Xenopus tadpole is very useful in analyzing the molecular mechanisms underlying appendage regeneration (Slack et al., 2004
...
Y Kagiyama N Gotouda K Sakagami K Yasuda M Mochii M Araki
DEVELOPMENT GROWTH & DIFFERENTIATION 47(8) 523-536 2005年10月 [査読有り]
Dorsal-ventral (DV) specification in the early optic vesicle plays a crucial role in the proper development of the eye. To address the questions of how DV specification is determined and how it affects fate determination of the optic vesicle, isol...
D Baldessari Y Shin O Krebs R Konig T Koide A Vinayagam U Fenger M Mochii C Terasaka A Kitayama D Peiffer N Ueno R Eils KW Cho C Niehrs
MECHANISMS OF DEVELOPMENT 122(3) 441-475 2005年3月 [査読有り]
We have undertaken a large-scale microarray gene expression analysis using cDNAs corresponding to 21,000 Xenopus laevis ESTs. mRNAs from 37 samples, including embryos and adult organs, were profiled. Cluster analysis of embryos of different stages...
Amputation of the larval tail of Xenopus injures the notochord, spinal cord, muscle masses, mesenchyme, and epidermis, induces the growth and differentiation of cells in those tissues, and results in tail regeneration. A dorsal incision in the lar...
DEVELOPMENT GROWTH & DIFFERENTIATION 50(3) 169-180 2008年4月
We examined several candidate posterior/mesodermal inducing molecules using permanent blastula-type embryos (PBEs) as an assay system. Candidate molecules were injected individually or in combination with the organizer factor chordin mRNA. Injecti...
DEVELOPMENT GROWTH & DIFFERENTIATION 50(2) 109-120 2008年2月
Tail regeneration in urodeles is dependent on the spinal cord (SC), but it is believed that anuran larvae regenerate normal tails without the SC. To evaluate the precise role of the SC in anuran tail regeneration, we developed a simple operation m...
DEVELOPMENT GROWTH & DIFFERENTIATION 49(2) 155-161 2007年2月
The tail of the Xenopus tadpole contains major axial structures, including a spinal cord, notochord and myotomes, and regenerates within 2 weeks following amputation. The tail regeneration in Xenopus can provide insights into the molecular basis o...
MECHANISMS OF DEVELOPMENT 123(10) 746-760 2006年10月
We succeeded in visualization of the primordial germ cells (PGCs) in a living Xenopus embryo. The mRNA of the reporter Venus protein, fused to the 3' untranslated region (UTR) of DEADSouth, which is a component of the germ plasm in Xenopus eggs, w...
所属学協会
日本動物学会
国際発生生物学会(International Society of Developmental Biologysts)
大学本部
理学研究科