Antimicrobial resistance (AMR) is a global health problem. Despite the enormous efforts made in the last decade, threats from some species, including drug-resistant Neisseria gonorrhoeae, continue to rise and would become untreatable. Th...
Low body temperature predicts a poor outcome in patients with heart failure, but the underlying pathological mechanisms and implications are largely unknown. Brown adipose tissue (BAT) was initially characterised as a thermogenic organ, ...
Ranjana Gupta   Xiao-Xi Li   Youngseob Lee   Mi Sook Seo   Yong-Min Lee   Sachiko Yanagisawa   Minoru Kubo   Ritimukta Sarangi   Kyung-Bin Cho   Shunichi Fukuzumi   Wonwoo Nam   
Chemical Science 13(19) 5707-5717 2022年4月 [査読有り]
Disproportionation of Cpd II models depends on the electron-richness of the porphyrin ligand; Cpd II with an electron-deficient ligand is difficult to disproportionate, whereas Cpd II with an electron-rich ligand readily disproportionates to form ...
Proceedings of the National Academy of Sciences 119(9) 2022年2月 [査読有り]
Significance
Light-driven chloride pumps have been identified in various species, including archaea and marine flavobacteria. The function of ion transportation controllable by light is utilized for optogenetics tools in neuroscience. Chloride p...
Structural information on protein dynamics is a critical factor in fully understanding the protein functions. Pump-probe time-resolved serial femtosecond crystallography (TR-SFX) is a recently established technique for visualizing the structural c...