Normal vibrational modes of heme have been analyzed using density functional theory, to assign a new Raman band observed at 312 cm(-1) in the CO-bound, active form of soluble guanylate cyclase. The conserved YxSxR motif is incorporated into the mo...
JOURNAL OF BIOLOGICAL CHEMISTRY 287(24) 19973-19984 2012年6月 [査読有り]
HemAT-Bs is a heme-based signal transducer protein responsible for aerotaxis. Time-resolved ultraviolet resonance Raman (UVRR) studies of wild-type and Y70F mutant of the full-length HemAT-Bs and the truncated sensor domain were performed to deter...
JOURNAL OF PHYSICAL CHEMISTRY LETTERS 2(17) 2212-2217 2011年9月 [査読有り]
Protein dynamics on the subnanosecond to microsecond time scale was investigated for the isolated heme domain of a gas sensor protein, EcDOS, with time-resolved ultraviolet resonance Raman (UVRR) spectroscopy. Rapid structural changes (<0.5 ns)...
Alexander Barabanschikov Alexander Demidov Minoru Kubo Paul M. Champion J. Timothy Sage Jiyong Zhao Wolfgang Sturhahn E. Ercan Alp
JOURNAL OF CHEMICAL PHYSICS 135(1) 015101 2011年7月 [査読有り]
Nuclear resonance vibrational spectroscopy (NRVS) reveals the vibrational dynamics of a Mossbauer probe nucleus. Here, Fe-57 NRVS measurements yield the complete spectrum of Fe vibrations in halide complexes of iron porphyrins. Iron porphine serve...
Yu Jin Choi Kyung-Bin Cho Minoru Kubo Takashi Ogura Kenneth D. Karlin Jaeheung Cho Wonwoo Nam
DALTON TRANSACTIONS 40(10) 2234-2241 2011年 [査読有り]
A copper(II)-hydroperoxo complex, [Cu(Me-6-tren)(OOH)](+) (2), and a copper(II)-cumylperoxo complex, [Cu(Me-6-tren)(OOC(CH3)(2)Ph)](+) (3), were synthesized by reacting [Cu(Me-6-tren)(CH3CN)](2+) (1) with H2O2 and cumyl-OOH, respectively, in the p...
Structural information on protein dynamics is a critical factor in fully understanding the protein functions. Pump-probe time-resolved serial femtosecond crystallography (TR-SFX) is a recently established technique for visualizing the structural c...
大学本部
理学研究科