tRNAの量的調節機構の解析
,核-細胞質間物質輸送 tRNAの細胞内動態 tRNAのスプライシング RNAの品質管理
,nuclear-cytoplasmic transport intracellular dynamics of tRNA tRNA splicing quality control of RNA
MOLECULAR BIOLOGY OF THE CELL 21(21) 3722-3734 2010年11月 [査読有り]
The unfolded protein response (UPR) is an essential signal transduction to cope with protein-folding stress in the endoplasmic reticulum. In the yeast UPR, the unconventional splicing of HAC1 mRNA is a key step. Translation of HAC1 pre-mRNA (HAC1(...
JOURNAL OF BIOLOGICAL CHEMISTRY 284(46) 31635-31646 2009年11月 [査読有り]
Mitochondrial protein traffic requires precise recognition of the mitochondrial targeting signals by the import receptors on the mitochondrial surface including a general import receptor Tom20 and a receptor for presequence-less proteins, Tom70. H...
The splicing of nuclear encoded RNAs, including tRNAs, has been widely believed to occur in the nucleus. However, we recently found that one of the tRNA splicing enzymes, splicing endonuclease, is localized to the outer surface of mitochondria in ...