Takagi K   Saeki Y   Yashiroda H   Yagi H   Kaiho A   Murata S   Yamane T   Tanaka K   Mizushima T   Kato K   
Biochemical and biophysical research communications 450(2) 1110-4 2014年7月 [査読有り]
Structure (London, England : 1993) 22(5) 731-43 2014年5月 [査読有り]
Proteasome formation does not occur due to spontaneous self-organization but results from a highly ordered process assisted by several assembly chaperones. The assembly of the proteasome ATPase subunits is assisted by four client-specific chaperon...
Several autophagy proteins contain an LC3-interacting region (LIR) responsible for their interaction with Atg8 homolog proteins. Here, we show that ALFY binds selectively to LC3C and the GABARAPs through a LIR in its WD40 domain. Binding of ALFY t...
JOURNAL OF BIOLOGICAL CHEMISTRY 285(20) 15159-15166 2010年5月
The ubiquitin-proteasome pathway is a major proteolytic system in eukaryotic cells and regulates various cellular processes. The 26 S proteasome, the central enzyme of this pathway, consists of a proteolytic core particle and two 19 S regulatory p...