衣斐義一

研究者氏名	衣斐義一
	エミヨシカズ
URL	http://www.sci.u-hyogo.ac.jp/life/biochem1/index-j.html
所属	兵庫県立大学
部署	大学院理学研究科
職名	准教授
学位	理学博士(九州大学)
J-Global ID	200901007585513876

プロフィール

九州大学大学院医学系研究科分子生命科学専攻博士課程

研究キーワード

細胞内局在化 ,肝臓 ,異物代謝 ,ABC輸送体 ,グルクロン酸転移酵素

研究分野

ライフサイエンス / 細胞生物学 /

受賞

2011年9月

Journal of Biochemistry/Oxford University Press, JB/OUPポスター賞
衣斐義一

論文

<123 4 5 >

Ontogenic isoform switching of UDP-glucuronosyltransferase family 1 in rat liver

Mariko Kishi Yoshikazu Emi Masao Sakaguchi Shin-ichi Ikushiro Takashi Iyanagi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 377(3) 815-819 2008年12月 [査読有り]

The liver undergoes dramatic changes in function during development. The development of UDP-glucuronosyltransferase family 1 (UGT1) isoforms was studied in livers from rats at 16-20days of gestation, at days 1, 2, 3, 4, and 7 of infancy, at days 1...

Human ABC transporter isoform B6 (ABCB6) localizes primarily in the Golgi apparatus.

Masashi Tsuchida Yoshikazu Emi Yuichiro Kida Masao Sakaguchi

Biochemical and biophysical research communications 369(2) 369-75 2008年5月 [査読有り]

Human ATP-binding cassette transporter isoform B6 (ABCB6) has been proposed to be situated in both the inner and outer membranes of mitochondria. These inconsistent observations of submitochondrial localization have led to conflicting interpretati...

Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans

Yoshihisa Kato Shin-ichi Ikushiro Yoshikazu Emi Sekihiro Tamaki Hiroshi Suzuki Toshiyuki Sakaki Shizuo Yamada Masakuni Degawa

DRUG METABOLISM AND DISPOSITION 36(1) 51-55 2008年1月

To clarify the UDP-glucuronosyltransferase (UGT) isoform(s) responsible for the glucuronidation of the thyroid hormone thyroxine (T-4) in the human liver, the T-4 glucuronidation activities of recombinant human UGT isoforms and microsomes from sev...

Thyroxine-metabolizing rat uridine diphosphate-glucuronosyltransferase 1A7 is regulated by thyroid hormone receptor

Yoshikazu Emi Shin-ichi Ikushiro Yoshihisa Kato

ENDOCRINOLOGY 148(12) 6124-6133 2007年12月 [査読有り]

Exposure of rats to microsomal enzyme inducers perturbs thyroid hormone (TH) homeostasis through a variety of mechanisms. Glucuronidation is an important metabolic pathway for TH and is catalyzed by uridine diphosphate-dibenzo-glucuronosyltransfer...

Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair

M Shimizu H Akter Y Emi R Sato T Yamaguchi F Hirose T Osumi

JOURNAL OF BIOCHEMISTRY 139(3) 563-573 2006年3月 [査読有り]

Perilipin is an adipocyte-specific protein associated with lipid droplets that is crucial for the regulation of storage and mobilization of lipids. We earlier reported that the mouse perilipin gene is regulated by peroxisome proliferator-activated...