Nitric oxide (NO) is generated in some biological systems. Due to its radical character, it exhibits high reactivity, but biological system can manage NO without sustaining any damage to bio-compounds in the cell. As a model system to understand h...
Samuel L Rose   Svetlana V Antonyuk   Daisuke Sasaki   Keitaro Yamashita   Kunio Hirata   Go Ueno   Hideo Ago   Robert R Eady   Takehiko Tosha   Masaki Yamamoto   S Samar Hasnain   
Science advances 7(1) 2021年1月
Copper-containing nitrite reductases (CuNiRs), encoded by nirK gene, are found in all kingdoms of life with only 5% of CuNiR denitrifiers having two or more copies of nirK Recently, we have identified two copies of nirK genes in several α-proteoba...
Marina Lučić   Dimitri A Svistunenko   Michael T Wilson   Amanda K Chaplin   Bradley Davy   Ali Ebrahim   Danny Axford   Takehiko Tosha   Hiroshi Sugimoto   Shigeki Owada   Florian S N Dworkowski   Ivo Tews   Robin L Owen   Michael A Hough   Jonathan A R Worrall   
Angewandte Chemie (International ed. in English) 59(48) 21656-21662 2020年11月
Obtaining structures of intact redox states of metal centers derived from zero dose X-ray crystallography can advance our mechanistic understanding of metalloenzymes. In dye-decolorising heme peroxidases (DyPs), controversy exists regarding the me...
M. Arif M. Jamali   Chai C. Gopalasingam   Rachel M. Johnson   Takehiko Tosha   Kazumasa Muramoto   Stephen P. Muench   Svetlana V. Antonyuk   Yoshitsugu Shiro   Samar S. Hasnain   
IUCrJ 7(3) 404-415 2020年5月 [査読有り]
<italic>Neisseria meningitidis</italic> is carried by nearly a billion humans, causing developmental impairment and over 100 000 deaths a year. A quinol-dependent nitric oxide reductase (qNOR) plays a critical role in the survival of the bacterium...
BIN MOHAMAD JAMALI Muhamad Arif   GOPALASINGAM Chai C.   JOHNSON Rachel M.   MUENCH Stephen P   ANTONYUK Svetlana V.   HASNAIN Samar S.   TOSHA Takehiko   MURAMOTO Kazumasa   SHIRO Yoshitsugu