Nitric oxide (NO) is generated in some biological systems. Due to its radical character, it exhibits high reactivity, but biological system can manage NO without sustaining any damage to bio-compounds in the cell. As a model system to understand h...
Samuel L Rose Svetlana V Antonyuk Daisuke Sasaki Keitaro Yamashita Kunio Hirata Go Ueno Hideo Ago Robert R Eady Takehiko Tosha Masaki Yamamoto S Samar Hasnain
Science advances 7(1) 2021年1月
Copper-containing nitrite reductases (CuNiRs), encoded by nirK gene, are found in all kingdoms of life with only 5% of CuNiR denitrifiers having two or more copies of nirK Recently, we have identified two copies of nirK genes in several α-proteoba...
Marina Lučić Dimitri A Svistunenko Michael T Wilson Amanda K Chaplin Bradley Davy Ali Ebrahim Danny Axford Takehiko Tosha Hiroshi Sugimoto Shigeki Owada Florian S N Dworkowski Ivo Tews Robin L Owen Michael A Hough Jonathan A R Worrall
Angewandte Chemie (International ed. in English) 59(48) 21656-21662 2020年11月
Obtaining structures of intact redox states of metal centers derived from zero dose X-ray crystallography can advance our mechanistic understanding of metalloenzymes. In dye-decolorising heme peroxidases (DyPs), controversy exists regarding the me...
M. Arif M. Jamali Chai C. Gopalasingam Rachel M. Johnson Takehiko Tosha Kazumasa Muramoto Stephen P. Muench Svetlana V. Antonyuk Yoshitsugu Shiro Samar S. Hasnain
IUCrJ 7(3) 404-415 2020年5月 [査読有り]
<italic>Neisseria meningitidis</italic> is carried by nearly a billion humans, causing developmental impairment and over 100 000 deaths a year. A quinol-dependent nitric oxide reductase (qNOR) plays a critical role in the survival of the bacterium...
BIN MOHAMAD JAMALI Muhamad Arif GOPALASINGAM Chai C. JOHNSON Rachel M. MUENCH Stephen P ANTONYUK Svetlana V. HASNAIN Samar S. TOSHA Takehiko MURAMOTO Kazumasa SHIRO Yoshitsugu
大学本部
理学研究科