We previously reported cloning of the Drosophila mitochondrial transcription factor A (D-mtTFA) gene, and characterization of a recombinant protein. In this report, the expression and distribution patterns of D-mtTFA during development are describ...
Kei-ichi Takata Gen Ishikawa Fumiko Hirose Kengo Sakaguchi
Nucleic acids research 30(17) 3795-808 2002年9月
We succeeded in cloning the gene, termed d-ddb1, for a Drosophila homolog of the p127 subunit of the human damage-specific DNA-binding protein, thought to recognize (6-4) photoproducts and related structures. In Drosophila, the gene product (D-DDB...
Hiroshi Asahara Sophie Tartare-Deckert Takeya Nakagawa Tsuyoshi Ikehara Fumiko Hirose Tony Hunter Takashi Ito Marc Montminy
Molecular and cellular biology 22(9) 2974-83 2002年5月
In a yeast two-hybrid screen to identify proteins that bind to the KIX domain of the coactivator p300, we obtained cDNAs encoding nucleosome assembly protein 1 (NAP-1), a 60-kDa histone H2A-H2B shuttling protein that promotes histone deposition. p...
H Higashiyama F Hirose M Yamaguchi YH Inoue N Fujikake A Matsukage A Kakizuka
CELL DEATH AND DIFFERENTIATION 9(3) 264-273 2002年3月 [査読有り]
We have successfully generated a Drosophila model of human polyglutamine (polyQ) diseases by the targeted expression of expanded-polyQ (ex-polyQ) in the Drosophila compound eye, The resulting eye degeneration is progressive and ex-polyQ dosage- an...
Molecular and Cellular Biology 21(21) 7231-7242 2001年11月 [査読有り]
<title>ABSTRACT</title>
The promoters of <italic>Drosophila</italic> genes encoding DNA replication-related proteins contain transcription regulatory element DRE (5′-TATCGATA) in addition to E2F recognition sites. A specific DRE-binding factor, D...
E Kwon Y Hayashi K Otsuki F Hirose Y Nishida MA Yoo M Yamaguchi
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1679(3) 256-262 2004年9月
Here we show that Armadillo and Pangolin (dTCF), downstream effectors of the Wingless (Wg) signal transduction pathway, activate transcription of the important DNA replication-related genes encoding Drosophila proliferating cell nuclear antigen (P...
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