Cell structure and function 48(1) 71-82 2023年3月 [査読有り]
ATP-binding cassette transporter isoform C7 (ABCC7), also designated as cystic fibrosis transmembrane conductance regulator (CFTR), is exclusively targeted to the apical plasma membrane of polarized epithelial cells. Although the apical localizati...
Voltage-dependent K+ (K-V) channels control K+ permeability in response to shifts in the membrane potential. Voltage sensing in K-V channels is mediated by the positively charged transmembrane domain S4. The best-characterized K-V channel, KvAP, l...
JOURNAL OF BIOCHEMISTRY 159(5) 539-551 2016年5月 [査読有り]
Many membrane proteins possessing hydrophobic transmembrane (TM) segments are cotranslationally integrated into the endoplasmic reticulum (ER) membrane. Various peroxisomal and mitochondrial membrane proteins escape the ER-targeting mechanism and ...
JOURNAL OF BIOCHEMISTRY 159(5) 497-508 2016年5月 [査読有り]
Various proteins synthesized by ribosomes are imported into specific organelles. To elucidate the behavior of protein domains during import, we developed a folding probe, in which the capsid protease (CP) domain of the Semliki Forest virus was con...
Kashiwayama, Y   Asahina, K   Shibata, H   Morita, M   Muntau, A. C   Roscher, A. A   Wanders, R. J. A   Shimozawa N   Sakaguchi, M   Kato, H   Imanaka, T