Hirofumi Inoue Mari Maeda-Yamamoto Atsushi Nesumi Takuji Tanaka Akira Murakami
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77(6) 1223-1228 2013年6月 [査読有り]
Our previous study indicated that a diet containing a high dose (1%) of green tea polyphenols (GTPs) disrupted liver and kidney function via a reduction in antioxidant enzyme and heat shock protein (HSP) levels in both colitis and non-treated ICR ...
Bokyung Sung Sahdeo Prasad Vivek R. Yadav Subash C. Gupta Simone Reuter Norio Yamamoto Akira Murakami Bharat B. Aggarwal
PLoS ONE 8(5) e64118 2013年5月 [査読有り]
Bone loss/resorption or osteoporosis is a disease that is accelerated with aging and age-associated chronic diseases such as cancer. Bone loss has been linked with human multiple myeloma, breast cancer, and prostate cancer and is usually treated w...
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 52(3) 215-227 2013年5月 [査読有り]
There is compelling evidence showing that dietary phytochemicals have exhibited pronounced bioactivities in a number of experimental models. In addition, a variety of epidemiological surveys have demonstrated that frequent ingestion of vegetables ...
We have recently developed a simplified analog of aplysiatoxin (aplog-1) as an activator of protein kinase C (PKC) with anti-proliferative activity like bryostain 1. To identify sites in aplog-1 that could be readily modified to optimize therapeut...
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