Aya Tanaka   Yoshiaki Kashimura   Eiichi Kuramochi   Koji Sumitomo   
APPLIED PHYSICS EXPRESS 7(1) 2014年1月 [査読有り]
To provide a platform for a nanobiodevice, we fabricated microcavities on a Si/SiO2 substrate covered by a thin SiO2 layer with nanohole arrays that we call a pepper shaker substrate. Fluorescence and atomic force microscopy images showed that the...
Tsukada, S.   Kasai, N.   Kawano, R.   Takagahara, K.   Fujii, K.   Sumitomo, K.   
NTT Technical Review 12(4) 2014年1月 [査読有り][招待有り]
We developed a conductive fiber by coating the surface of silk or synthetic fiber with a conductive polymer and fabricated wearable electrodes to achieve long-term biosignal monitoring. This new bioelectrode made of a complex conductive material i...
Aya Tanaka   Hiroshi Nakashima   Yoshiaki Kashimura   Koji Sumitomo   
JAPANESE JOURNAL OF APPLIED PHYSICS 53(1) 2014年1月 [査読有り]
We successfully sealed a gel-confined microwell array on a Si substrate with a lipid membrane by rupturing giant unilamellar vesicles. Atomic force microscope measurements suggested that gel with a hillock structure supported lipid membranes gentl...
Ali D. Malay   Jonathan G. Heddle   Satoshi Tomita   Kenji Iwasaki   Naoyuki Miyazaki   Koji Sumitomo   Hisao Yanagi   Ichiro Yamashita   Yukiharu Uraoka   
NANO LETTERS 12(4) 2056-2059 2012年4月 [査読有り]
Gold nanoparticles are generally considered to be biologically inactive. However, in this study we show that the addition of 1.4 nm diameter gold nanoparticle induces the remodeling of the ring-shaped protein TRAP into a hollow, capsid-like config...
Biosensors and Bioelectronics 31(1) 445-450 2012年1月 [査読有り]
For the functional analysis of ion channel activity, an artificial lipid bilayer suspended over microwells was formed that ruptured giant unilamellar vesicles on a Si substrate. Ca2+ion indicators (fluo-4) were confined in the microwells by sealin...