We developed a simple, rapid, and label-free method to obtain the ratio of cells with a specific surface protein from heterogeneous cell populations, and applied it to estimate the cell differentiation states. The repulsive force of negative diele...
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 37(2) 229-232 2021年2月 [査読有り]
The electrorotation (ROT) rates of K562 cells accompanied by erythroid differentiation were estimated to identify the differentiation status by using a novel electrorotation device with a microwell arranged on polynomial electrodes. Successive est...
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences 257-258 2021年
We have developed the effective electrofusion of cells with different sizes in microwells with a rectangle shape. B-cells were captured by positive dielectrophoresis on the right side of the microwell and myeloma cells on the left side to form pai...
Cell microarrays which sectionalized cells into microwells are powerful tool for elucidating exhaustively functions of cells at single cell level. However, there are some difficulties in taking advantages of the cell array. At firs...
We provide a novel method to discriminate the cells binding with molecules immobilized on a glass substrate by using the repulsive force of negative dielectrophoresis. The device consists of a lower substrate with interdigitated (IDA) patterns (12...
Analytical Sciences, Best Paper Award in 2021,Selective Trapping and Retrieval of Single Cells Using Microwell Array Devices Combined with DielectrophoresisMisaki HATA Masato SUZUKI Tomoyuki YASUKAWA