Live cell imaging is a powerful technique to study cellular dynamics in vivo during animal development and regeneration. However, few live imaging methods have been reported for studying planarian regeneration. Here, we developed a simple method f...
Nishimura O   Hosoda K   Kawaguchi E   Yazawa S   Hayashi T   Inoue T   Umesono Y   Agata K   
Adult planarians possess somatic pluripotent stem cells called neoblasts that give rise to all missing cell types during regeneration and homeostasis. Recent studies revealed that the Yorkie (Yki)/Yes-associated protein (YAP) transcriptional coact...
New Principles in Developmental Processes 9784431546344 71-83 2014年11月 [査読有り]
Planarians have a long history of attracting many biologists for their amazing regenerative ability, which absolutely depends on a unique population of somatic pluripotent stem cells called neoblasts that are distributed throughout the body. After...
Planarians have strong regenerative abilities derived from their adult pluripotent stem cell (neoblast) system. However, the molecular mechanisms involved in planarian regeneration have long remained a mystery. In particular, no anterior-specifyin...
Methods in molecular biology (Clifton, N.J.) 1487 303-315 2017年
Planarians are an ideal model in which to study stem cell-based regeneration. After amputation, planarian pluripotent stem cells surrounding the wound proliferate to produce the regenerative blastema, in which they differentiate into the missing t...