Yoshihiko Umesono Junichi Tasaki Yui Nishimura Martina Hrouda Eri Kawaguchi Shigenobu Yazawa Osamu Nishimura Kazutaka Hosoda Takeshi Inoue Kiyokazu Agata
Nature 500(7460) 73-6 2013年8月 [査読有り]
The planarian Dugesia japonica can regenerate a complete individual from a head, trunk or tail fragment via activation of somatic pluripotent stem cells. About a century ago, Thomas Hunt Morgan attempted to explain the extraordinary regenerative a...
The European journal of neuroscience 34(6) 863-9 2011年9月 [査読有り]
A unique aspect of planarians is that they can regenerate a brain from somatic pluripotent stem cells called neoblasts, which have the ability to produce themselves (self-renew) and to give rise to all missing cell types during regeneration. Recen...
Development (Cambridge, England) 138(12) 2417-27 2011年6月 [査読有り]
The robust regenerative ability of planarians depends on a population of somatic stem cells called neoblasts, which are the only mitotic cells in adults and are responsible for blastema formation after amputation. The molecular mechanism underlyin...
The robust regenerative abilities of planarians absolutely depend on a unique population of pluripotent stem cells called neoblasts, which are the only mitotic somatic cells in adult planarians and are responsible for blastema formation after ampu...
Methods in molecular biology (Clifton, N.J.) 1487 303-315 2017年
Planarians are an ideal model in which to study stem cell-based regeneration. After amputation, planarian pluripotent stem cells surrounding the wound proliferate to produce the regenerative blastema, in which they differentiate into the missing t...
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